Clicky

Ok

En poursuivant votre navigation sur ce site, vous acceptez l'utilisation de cookies. Ces derniers assurent le bon fonctionnement de nos services. En savoir plus.

01/10/2024

REBOA préhospitalier: Une mortalité inchangée à 30 j, désillusion ?

Prehospital Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Exsanguinating Subdiaphragmatic Hemorrhage

 
----------------------------------
L'occlusion endovasculaire de l'aorte est proposée pour l'arrêt des hémorragies sous-diaphragmatique responsable d'exsanguination. Cette technique suscite un grand intérêt en préhospitalier et chez les militaires (1). Pour autant faisable , ne signifie pas à faire. En effet elle a des contraintes techniques de pose notamment liées à l'accès vasculaire, l'identification du niveau d'occlusion et surtout un impératif de chirurgie rapide après sa pose, idéalement 20 minutes. Les retours d'expérience montrent que si un REBOA peut être posé en préhospitalier, il n'améliore probablement pas la survie des patients à long terme. C'est ce que montre ce travail qui doit être mis en parallèle avec les résultats de l'enquête UK-REBOA Randomized Clinical Trial qui, bien que discutés (2), va dans le même sens.
 
En l'état actuel des choses, il semble que cette technique ne peut pas être recommandée, du moins généralisée (3). 
 

Importance  

Hemorrhage is the most common cause of preventable death after injury. Most deaths occur early, in the prehospital phase of care.

Objective  

To establish whether prehospital zone 1 (supraceliac) partial resuscitative endovascular balloon occlusion of the aorta (Z1 P-REBOA) can be achieved in the resuscitation of adult trauma patients at risk of cardiac arrest and death due to exsanguination.

Design, Setting, and Participants  

This was a prospective observational cohort study (Idea, Development, Exploration, Assessment and Long-term follow-up [IDEAL] 2A design) with recruitment from June 2020 to March 2022 and follow-up until discharge from hospital, death, or 90 days evaluating a physician-led and physician-delivered, urban prehospital trauma service in the Greater London area. Trauma patients aged 16 years and older with suspected exsanguinating subdiaphragmatic hemorrhage, recent or imminent hypovolemic traumatic cardiac arrest (TCA) were included. Those with unsurvivable injuries or who were pregnant were excluded. Of 2960 individuals attended by the service during the study period, 16 were included in the study.

Main Outcomes and Measures  

The main outcome was the proportion of patients in whom Z1 REBOA and Z1 P-REBOA were achieved. Clinical end points included systolic blood pressure (SBP) response to Z1 REBOA, mortality rate (1 hour, 3 hours, 24 hours, or 30 days postinjury), and survival to hospital discharge.

Results  

Femoral arterial access for Z1 REBOA was attempted in 16 patients (median [range] age, 30 [17-76] years; 14 [81%] male; median [IQR] Injury Severity Score, 50 [39-57]). In 2 patients with successful arterial access, REBOA was not attempted due to improvement in clinical condition. In the other 14 patients (8 [57%] of whom were in traumatic cardiac arrest [TCA]), 11 successfully underwent cannulation and had aortic balloons inflated in Z1.

 

m_soi240044t2_1725986252.42187.png?Expires=1730758218&Signature=LGB13pPpQsEFQSiBvXmI2pvCJUc4hyO9AdelHLfFwbeYj5AblEYqy-h3JS5lyxi4cnj4Ekj3wMhNJ0K3YPsMw9at0iyZJ-2auitXtDoHIIVSUV1VxyTvh3y7wLuv7qrGYIhsf6kHN8kDuTsVZne9VgPYPyO0f0w1rWVXWc8EFgfbg9b~8v5C2kjgI6s~kPgdpPpwERsnsqaOAiF-hYj6ZncyV3446NBm4V17bBpIEVoXbixpykpIZ24d9dWQS-wyqfoMtvVrC8oFXbHLetLs~iy8HY28enoypZoY2XBPMam-9KmOxNlIe~Vn-3Vdx9H2LYRm0JksiewHj93Dr3jpGQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA

The 3 individuals in whom cannulation was unsuccessful were in TCA (failure rate = 3/14 [21%]). Median (IQR) pre-REBOA SBP in the 11 individuals for whom cannulation was successful (5 [46%] in TCA) was 47 (33-52) mm Hg. Z1 REBOA plus P-REBOA was associated with a significant improvement in BP (median [IQR] SBP at emergency department arrival, 101 [77-107] mm Hg; 0 of 10 patients were in TCA at arrival). The median group-level improvement in SBP from the pre-REBOA value was 52 (95% CI, 42-77) mm Hg (P < .004). P-REBOA was feasible in 8 individuals (8/11 [73%]) and occurred spontaneously in 4 of these. The 1- and 3-hour postinjury mortality rate was 9% (1/11), 24-hour mortality was 27% (3/11), and 30-day mortality was 82% (9/11). Survival to hospital discharge was 18% (2/11). Both survivors underwent early Z1 P-REBOA.

Conclusions and Relevance  In this study, prehospital Z1 P-REBOA is feasible and may enable early survival, but with a significant incidence of late death.

Poser un garrot: Pas n'importe comment !

Who needs a tourniquet? And who does not? Lessons learned from a review of tourniquet use in the Russo-Ukrainian war

Butler F et All. Journal of Trauma and Acute Care Surgery 97(2S):p S45-S54, August 2024

----------------------

rexfeatures_1307645b.jpg

Clic sur l'image pour accéder à la publication

Un point de situation important à lire. Il met en exergue le danger des garrots posé de manière indue avec deux trois enjeux de formation:

- La reconnaissance du caractère massif d'une hémorragie justifiant de la pose d'un garrot

 

ArticleViewerPreview.01586154-202408001-00011.F3.jpeg

 

- La reconnaissance des non indications de pose de garrot: 

ArticleViewerPreview.01586154-202408001-00011.F6.jpeg

 

- La réévaluation dans les 02h00 de l'indication du garrot et de sa conversion éventuelle.

----------------------